Insomnia and Drowsiness. Read on to know the causes of muscle weakness and how you can mitigate the risk. How they can cause fatigue: Researchers have long known that some people who take antibiotics experience feelings of tiredness and extreme fatigue, but it’s still not clear exactly why. For older patients, a benzothiazepine calcium channel blocker, such as diltiazem (Cardizem), is often the best choice. Learn about weakness in legs and when to see a doctor. Kidney disease also causes a build-up of poisonous substances (toxins) in the blood because the poorly functioning kidneys process these toxins more slowly. Long-term use of prescribed oral steroids also causes muscle weakness and wasting. This leaflet looks at types of muscle weakness and discusses the wide range of problems which may cause them. This often goes with muscle tiredness but is particularly seen in some uncommon conditions such as myasthenia gravis and myotonic dystrophy. They’re also used to treat or prevent infections that can complicate surgery or other medical procedures. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. They will also be able to tell you if there are any serious concerns about your symptoms and will be able to refer you for further testing if required. How it began and long you have had it for. This can recover partially but does not always do so. In addition, as diabetes progresses, the blood supply to small nerves is lost. Are your medications making you feel sleepy? It reduces the ability of the blood to carry oxygen to muscles, so they tire more easily. This condition is characterized by extreme fatigue that can’t be explained by any underlying medical condition.). They will then need to test your nerves to see whether the muscles are getting the right signals to act. Infections and illnesses are amongst the most common causes of temporary muscle fatigue. Why they’re prescribed: Antihistamines are used to relieve or prevent the symptoms of allergic disorders (such as hay fever) or the common cold. It may occur as a result of an inactive (sedentary) lifestyle. Examples are organophosphates (used in farming and sadly as chemical weapons) and botulinum toxin (used in Botox®, both for cosmetic and for therapeutic reasons). Interferon - used in some cancers and for multiple sclerosis (MS). Long-term effects also may include muscle weakness. It can be temporary or long-lasting (from seconds or minutes to months or years). Alternatives: Talk with your doctor or other health care provider about adjusting your antidepressant dose (side effects are often dose-related) or whether nondrug therapies might work just as well or better for you than a drug. What could be causing your pins and needles? Muscle fatigue is a condition where the muscle is not able to exert the required force normally when it has to. What causes muscle weakness. It may last many months, although complete recovery is usual. The condition usually goes away after a few years. Why they’re prescribed: While antidepressants are typically used to treat depression, they’re also frequently prescribed for anxiety disorders, eating disorders, obsessive compulsive disorder, chronic pain, smoking cessation and some hormone-mediated disorders, such as severe menstrual cramps. In this article, you'll learn what is Muscle Weakness. If you have a minor bacterial infection, ask your physician if an antibiotic is really needed and if a natural alternative might do the trick. The situation arises due to genetic reasons or due to heavy exercise. Other uncommon nerve conditions:Multiple sclerosis (MS): this is caused by damage to nerves in the brain and spinal cord and can cause sudden paralysis. If so, you’re not alone. It can happen, for example, following stroke. Muscular dystrophies: these are inherited diseases which affect muscles. More than 20 million Americans take prescription PPIs, including esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec) and pantoprazole (Protonix), some of which are available over the counter. Note: anxiety and depression are both conditions which tend to cause a sense of tiredness and 'fatigability' rather than true weakness. Fatigue is also one of the most common side effects that occurs with aliskiren (Tekturna, Tekturna HCT), which belongs to a newer class of drugs called renin inhibitors. If it is not completely reversed after surgery, the muscle relaxation effects might lead to remaining muscle weakness, breathing problems, lung infection and delayed recovery.Neostigmine and other medications from the same drug family are currently used to restore muscle function after surgery. Remember you are carrying a weight on the front. When this kind of weakness occurs the muscles are often floppier than usual and reduced in bulkiness. This is because some conditions tend to cause one type of weakness rather than another. Even though recovery is usual, if inflammation is severe (such as a bad bout of influenza), the weakness can last quite a while. AARP is a nonprofit, nonpartisan organization that empowers people to choose how they live as they age. That’s an important sign that your fatigue could be drug-induced. Try our Symptom Checker Got any other symptoms? Also, red yeast rice, a supplement first used in traditional Chinese medicine, has been found to be almost as effective as some of the moderate statins when used for short periods of time. Comments: 0. Muscles are not inflamed but tire very easily. This is usually through muscle inflammation. Any advice or information provided should not be followed in lieu of a personal consultation with a trained medical professional. receive communications related to AARP volunteering. The term muscle weakness can be used to describe several different things. Many chronic diseases commonly cause muscle weakness. CFS also causes psychological weariness, with other activities like reading and socialising also becoming exhausting. These range from the very common to the very rare. Medications that can cause muscle cramps include: Furosemide (Lasix), hydrochlorothiazide (Microzide), and other diuretics ("water pills") that remove fluid from the body Problems of the balance of salts in the body, including dehydration through not drinking enough, cause muscle tiredness. This condition resembles CFS. When you feel them they may be floppy and a little reduced in bulk. Smoking can indirectly weaken muscles. Each fibre is just as strong but there aren’t so many of them and they don’t contract so effectively. The difference between these three types of muscle weakness is often vague and you can have more than one of them. As we age, our muscles tend to lose strength and bulk and they become weaker. Examples include: Myotonic dystrophy: this is a rare genetic muscle disorder in which muscles become extremely tired. (For instance, in older patients, especially, these drugs increase the risk of heart failure.). Chronic fatigue has many causes, including illnesses such as anemia and multiple sclerosis as well as depression and other psychiatric disorders. Muscle weakness is a common complaint among patients presenting to the family physician’s office 1).Although the cause of muscle weakness occasionally may be apparent, often it is unclear, puzzling the physician and frustrating the patient. Is it safe to delay your period for your holiday? In CFS, muscles are not usually wasted and they may have normal strength on testing. Examples of medications that can cause muscle weakness include: amiodarone (Cordarone) antithyroid medications, such as methimazole (Tapazole) or propylthiouracil 31 years experience Psychiatry. People with other symptoms, such as fatigue (tiredness, feeling exhausted), sleepiness, or depression, will often say they feel weak and it can be hard to distinguish some of these from actual muscle weakness. However, exercise is still beneficial and it is still possible to increase muscle power and strength with a careful and safe exercise routine. In some conditions this is due to reduced blood and nutrient supply to muscles: Peripheral arterial disease: this is caused by narrowing of the arteries, usually due to the build-up of cholesterol. The muscle isn't genuinely weaker, it can still do its job but it takes you more effort to manage it. Be aware, though, that omega-3s can slightly raise levels of LDL or bad cholesterol, and other research has shown these may increase the risk of prostate cancer. Information contained in the Ask the Pharmacist column by Armon B. Neel Jr. is intended to help individuals and their families become more informed about medication usage and interactions, and be better health care consumers. Certain medications, chemicals, toxins or substances may possibly be underlying causes of Muscle weakness. Weakness in the legs may have many potential causes, including autoimmune or neurological conditions. At whatever age you decide to improve your fitness, a sensible training regime is essential. Causes for leg weakness range in severity, so it's important to pay attention to your symptoms and talk to your doctor. Muscle wasting will eventually occur: muscles become less chunky and more floppy. Disruptions in the body’s secretion of the stress hormone cortisol, for example, have been closely linked to fatigue symptoms. Let us know the causes of muscle fatigue. Why they’re prescribed: Proton pump inhibitors are used to treat gastroesophageal reflux disease (GERD) and other similar disorders. During and just after pregnancy, high levels of steroids in the blood, together with a tendency to be lacking in iron (anaemia), can cause a feeling of muscle tiredness. This is also the result of a pain. It may be due to a reduction in the speed with which the muscle can get its energy supply. It has many causes, including heavy periods, poor diet, blood loss, pregnancy, genetic conditions, infections and cancers. Muscle weakness is commonly due to lack of exercise, ageing, muscle injury or pregnancy. Muscle weakness is the lack of muscle or physical strength. Statins, such as simvastatin are one class known to do this. Patients often feel enormous effort is needed for muscle activity which they would previously have found easy. Why they’re prescribed: Antibiotics are used to treat health conditions caused by bacteria, including ear and skin infections, urinary tract infections, food poisoning, pneumonia, meningitis and other serious illnesses. In some people the process takes even longer. Why they’re prescribed: Benzodiazepines, commonly known as tranquilizers, are used to treat a variety of anxiety disorders, agitation and muscle spasms, and to prevent seizures. Patients often show signs of depression and poor sleep. Like anxiety, it stimulates the production of chemical substances (hormones) in the body which respond to pain and injury. again. Whilst most people accept this as the natural consequence of age - particularly great age - it is frustrating to be unable to do the things you could manage when younger. How they can cause fatigue: Diuretics can interfere with the balance of electrolytes —including sodium, potassium and chloride — in your body. Lack of muscle fitness (deconditioning) is one of the most common causes of muscle weakness. what meds cause weakness. Neurological conditions: muscle weakness can be caused by cerebrovascular disease such as stroke and brain haemorrhage and spinal injury. Weakness may be generalized or may affect one muscle or muscle group exclusively. This can be so extreme that patients can't keep their eyelids lifted and speech can become slurred. Upgrade to Patient Pro Medical Professional? This is an expected side-effect which anyone on long-term treatment is likely to experience. Check the safety information that comes with your blood pressure medications and you may well see “extreme tiredness” listed as a side effect. Hence, they become possible underlying causes of Muscle weakness but are often misdiagnosed or overlooked as a cause. These range from common to rare, serious to minor, temporary to permanent. You will be asked to register or log in. Older people generally should not use diphenhydramine (Benadryl) — found in any sleep aid with a name ending in “PM” — because of its powerful sedative effects, which dramatically increase the risk of falls and bone fractures. If you have muscle weakness and visit your doctor, they will first need to know the following: Your doctor will need to examine you to see which muscles are affected and whether you have true or perceived muscle weakness. This type of weakness is often seen in people who have chronic fatigue syndrome, sleep disorders, depression, and chronic heart, lung, and kidney disease. One common medication that may cause mild-to-moderate muscle aches and weakness as a side effect is a statin, which is used to lower cholesterol. Some researchers have also suggested that statins interfere with the production of energy in cells in the same way that they interfere with the production of cholesterol. If you are experiencing muscle pain or weakness, it could be because you have a thyroid condition. Alternatives: The FDA has advised doctors and other health care providers to obtain serum magnesium levels before prescribing PPIs and then periodically thereafter. Tell your provider about any medical conditions you have. Muscles which become partially or completely paralysed lose their normal strength and will eventually waste. Addison's disease is a rare condition of underactivity of the adrenal gland, leading to a shortage of steroids in the blood and to abnormalities of the blood’s salts. To get the best treatment, come in to Complete Care Health Centers and see one of our providers today. Physically inactive people can lose as much as 3% to 5% of their muscle mass each decade after age 30. This can result in symptoms like weakness, amnesia, nerve pain and symptoms of heart failure. COVID-19 coronavirus: what is an underlying health condition? Fortunately, most cases of muscle weakness which lack obvious cause are reversible. Both of these conditions result in weakened muscles which cannot move the usual load. But it’s also often a side effect of drugs previously prescribed for other conditions. There is an even wider range of possible causes. Once you confirm that subscription, you will regularly   Coping strategies for easing muscle pain, regardless of the cause, may be useful in the meantime: massage, warm baths, and gentle exercise, for example. In a small proportion of cases of rheumatoid arthritis, muscle weakness and tiredness may be the only sign of the disease for some considerable time. Under your doctor’s guidance, you’ll gradually drop the dose in 20 mg increments, with 10 to 15 days between each taper, until you are completely off the drug. So, supervision is sensible, especially at first. 8  CFS is sometimes triggered by certain viral infections such as glandular fever (Epstein-Barr virus) and flu (influenza) but it is poorly understood. In the next 24 hours, you will receive an email to confirm your subscription to receive emails In untreated hypothyroidism, muscle degeneration and wasting can develop. It's always good to stay fit, whatever your age. Weight loss is common but the symptoms are often vague. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Beriberi is a low level of vitamin B1 that can cause damage to the heart, brain, and nerves. Because antidepressants may also worsen fatigue brought on by another condition, teasing out causes is often difficult. You might also want to explore switching drugs, especially if you’re older and taking one of the tricyclic antidepressants, which are considered to be potentially inappropriate drugs for older people. It can also occur with long-term conditions such as diabetes or heart disease. Older people generally should not use this drug because their renal systems are unable to efficiently clear it, allowing the drug to build up in the body. Calcium helps muscles contract, but when calcium leaks from muscle cells unintentionally, it can damage your muscle cells which causes muscle pain. There are many different kinds of antidepressants, including tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs), selective serotonin re-uptake inhibitors (SSRIs), dopamine antagonists and lithium, among others. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Nerve studies to make sure the nerves are conducting properly. Steroid or heart medicine, or muscle relaxers; Alcohol or illegal drugs; Lack of movement, such as from wearing a cast or splint, or being on bed rest; How is the cause of weakness diagnosed? related to AARP volunteering. Most list tiredness and drowsiness among the potential side effects; some list weakness. What you need to know about post-viral fatigue. Alternatives: Talk with your doctor or other health care provider about switching to another type of blood pressure medication. The muscle is not working properly - it has become abnormal. This is because if the nerve to a muscle fibre stops working, the muscle fibre can’t work either and it will become floppy and eventually shrivel. ... What causes muscle twitches with no other symptoms? They often have difficulty in starting and stopping movements and they are often depressed. It can progress to permanent changes if the medicines are not stopped. This is reassuring, as it means the chance of recovery to completely normal function is very high. Fatigue is also a listed side effect of fexofenadine (Allegra), another popular antihistamine, though perhaps less than other such drugs. For details see our conditions. Many medicines can cause muscle weakness and muscle damage as a side-effect or an allergic reaction. If you stop suddenly, you risk having GERD come back with more severe symptoms. Heart disease - particularly heart failure: this can cause easy tiring of the muscles through a reduction in blood supply at times of high demand. Medicines in common use which can occasionally do this include statins (used to lower cholesterol levels), some antibiotics (including ciprofloxacin and penicillin) and anti-inflammatory painkillers (such as naproxen and diclofenac). In chronic pain, true weakness can result, as muscles may not be used due to pain and discomfort. Gemfibrozil is another. Whether you are otherwise well, are losing weight or have travelled abroad recently. Diseases of the neuromuscular system, injuries, metabolic diseases, and toxins can all cause of measurable muscle weakness. Finally, people with diabetes also have an increased tendency to narrowing of the arteries (see 'Peripheral arterial disease', above). It's one of the reasons doctors try to avoid putting patients on long-term steroids if possible. Muscle weakness can also be caused by low levels of potassium and other electrolytes within muscle cells. What medicines or other drugs you have been taking and whether there are any muscle problems in your family. How they can cause fatigue: Benzodiazepines can cause sedation and fatigue by dampening activity in key parts of the central nervous system (CNS). Some recovery is possible but it will be slow and may not be complete. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. However, most can be improved by exercise and physiotherapy. They are coauthors of Are Your Prescriptions Killing You?, published by Atria Books. Muscle weakness can occur due to various factors like poor physical conditioning, intense workout, and malnutrition. Cancers can cause muscle damage directly but the presence of cancer anywhere in the body can also cause generalised muscle tiredness. Leg weakness can also result from neuromuscular diseases, such as myasthenia gravis and multiple sclerosis. Muscle weakness is a common complaint but the word weakness has a wide range of meanings, including tiredness, reduced power and failure to work at all. If muscle aches do occur with a statin, they generally begin within six months of starting the drug and resolve within approximately two months (on average) of stopping the drug. He or she will test … A natural benefit: Omega-3 fatty acids are also thought to be natural fatigue fighters. Alternatives: Newer-generation antihistamines such as loratadine (Claritin) and cetirizine (Zyrtec) are better tolerated by older patients and present a lower risk for fatigue. to search for ways to make a difference in your community at Injury recovery times are much longer with great age, balance is often impaired and thinner bones are easily broken. Your healthcare provider will ask when your signs and symptoms started and what makes your weakness worse. It’s important that you do not discontinue them on your own. Could one or more of the medications you’re taking be making you feel listless or lethargic? The weakness affects only the muscles served by the irritated or compressed nerve. Drug interactions causing Muscle weakness: When combined, certain drugs, medications, substances or toxins may react causing Muscle weakness as a symptom. However, antidepressants may also cause insomnia, notes the National Institute of Mental Health 2. Chronic lung disease: lung conditions such as chronic obstructive pulmonary disease (COPD) cause a reduction in the ability of the body to take in oxygen. Localised pain is the primary symptom but weakness also results. Motor neurone disease (MND): this is a progressive disorder of the nerves which affects all parts of the body. What are the differences between colds, flu and COVID-19? Muscle weakness in the muscles you are talking about feeling weakness in, like from pushups (triceps, deltoids, maybe biceps and trapezius) are associated with hypo and hyperthyroidism though, so I think you're on the right track to look in to your thyroid hormone level as a cause, but I can't say it is definitely one of those, or which one it is. Medications used to lower thyroid hormones, such as methimazole and propylthiouracil also can cause muscle weakness and wasting. Botulism, a rare and serious illness caused by Clostridium botulinum bacteria, can also lead to muscle weakness. Muscle weakness is not usually the first sign of a cancer but occurs later in the condition. You must be logged in to leave a comment. Causes Of Muscle Weakness. A substance called myoglobin within the muscle cells that is released can result in severe kidney damage and even kidney failure. Anxiety: generalised tiredness can be caused by anxiety. Similarly, the package insert for cephalexin (Keflex, Keftabs, Panixine, Biocef, Zartan) lists fatigue as a potential side effect. The provider’s terms, conditions and policies apply. They may want to watch you walk. In studies, the side effects include fatigue, lethargy and weakness. How they can cause fatigue: Antihistamines are CNS depressants. It’s important to remember that it takes older people up to three times longer than younger people to flush these drugs out of their bodies. Chronic pain: a general effect on energy levels can result from chronic pain. In this condition a shortage of thyroid hormone leads to generalised tiredness. They will check to see whether your muscles are tender to touch (which suggests they are inflamed) or unusually 'fatigable'. 7. They may need to perform blood tests to look for abnormalities of hormones, salts and blood cells. Corticosteroids may be needed as treatment as well. An omega-3 fish oil supplement may help to lower your blood pressure, too. You can also progress from one to another. These medications are anticholinesterase drugs and are administered either orally or via injection. It is also seen in a condition called muscular dystrophy (discussed further below). Read more below to learn 9 possible reasons your legs feel weak and questions your doctor may ask to evaluate your condition. You are leaving AARP.org and going to the website of our trusted provider. Even rarer, mitochondrial diseases which occur when the energy systems inside muscle cells don’t work properly. Muscle Weakness Diseases & Disorders: Symptoms, Causes And Treatment I. Muscle weakness is rarely the only sign of serious underlying disease. This may be severe in extreme cases, such as dehydration during a marathon. Anaemia often 'creeps' on quite slowly, so that significant muscle tiredness and breathlessness develop before the condition is diagnosed. Are you noticing persistent weakness in your legs? Medicines in common use which can occasionally do this include statins (used to lower cholesterol levels ), some antibiotics (including ciprofloxacin and penicillin) and anti-inflammatory painkillers (such as naproxen and diclofenac ). Muscle relaxation is required to facilitate some surgical procedures. What Is Muscle Weakness. Smoking causes narrowing of the arteries, leading to peripheral arterial disease. This can lead to lower back pain if you don't adapt what you do to take account of your altered posture. Ask the Pharmacist is written by Armon B. Neel Jr., PharmD, CGP, in collaboration with journalist Bill Hogan. The blood supply to the muscles is slowed and this becomes particularly noticeable with exercise, as it can't keep up with the demand. This can be severe and difficult to reverse. Further, it talks about the causes and symptoms of Muscle Weakness, along with the diagnosis, tests, and treatment of Muscle Weakness. Heart Drugs Commonly prescribed benzodiazepines include alprazolam (Xanax), clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan) and temazepam (Restoril). Prolonged use of certain drugs may also result in muscle weakness. Please return to AARP.org to learn more about other benefits. And if you’ve been prescribed an antipsychotic to help you sleep or for some other off-label use, you’d be well-advised to seek out more proven, safer treatments for your symptoms. Muscular disorders, such as muscular dystrophy and dermatomyositis, are also common causes of muscular weakness. 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